Ammonium Hydroxide → 2-Oxoindoline-5-sulfonamide
反応式
Cl[S:2]([C:5]1[CH:6]=[C:7]2[C:11](=[CH:12][CH:13]=1)[NH:10][C:9](=[O:14])[CH2:8]2)(=[O:4])=[O:3].[OH-].[NH4+:16]>C(O)C>[NH2:16][S:2]([C:5]1[CH:6]=[C:7]2[C:11](=[CH:12][CH:13]=1)[NH:10][C:9](=[O:14])[CH2:8]2)(=[O:4])=[O:3]参加物
4
実験手順
5-Chlorosulfonyl-2-oxindole (2.1 g) was added to 10 mL of ammonium hydroxide in 10 mL of ethanol and stirred at room temperature overnight. The mixture was concentrated and the solid collected by vacuum filtration to give 0.4 g (20% yield) of the title compound as an off-white solid.
後処理
- concentrationThe mixture was concentrated
- filtrationthe solid collected by vacuum filtration
出典と根拠
- ORDレコード
- ord-2520af5761ac4f8b8d7b07549287ce02
- 出典データセット
- uspto-grants-2005_02
- 特許番号
- US06855730B2
反応ノート
読み込み中…