化工社化工社 化学情報印刷レポート · 研究参考用
Methyl 4-(chlorocarbonyl)benzoate → 5-(4-Methoxycarbonylbenzamido)-2-oxindole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methyl 4-(chlorocarbonyl)benzoate | HCID 81850 | — |
| 反応物 | 5-Amino-2-oxindole | HCID 2773213 | — |
| 溶媒 | Pyridine | HCID 1049 | — |
| 生成物 | 5-(4-Methoxycarbonylbenzamido)-2-oxindole | HCID 23289962 | 81% |
反応手順
A mixture of 82.0 mg 5-amino-2-oxindole and 131.0 mg 4-methoxycarbonylbenzoyl chloride in pyridine was stirred at room temperature for 3 hr and poured into ice water. The precipitate was filtered, washed with water and dried in a vacuum oven to give 138.0 mg of 5-(4-methoxycarbonylbenzamido)-2oxindole (81% yield).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06855730B2 |
| 出典データセット | uspto-grants-2005_02 |
| ORD ID | ord-1c489b6e3bdf42119d09d797f8064076 |
| 出典メモ | uspto-grants-2005_02 |