P-Anisidine → 4-cyano-N-(4-methoxyphenyl)benzamide

反応式

[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([NH2:9])=[CH:5][CH:4]=1.[C:10]([C:12]1[CH:20]=[CH:19][C:15]([C:16](O)=[O:17])=[CH:14][CH:13]=1)#[N:11]>>[C:10]([C:12]1[CH:20]=[CH:19][C:15]([C:16]([NH:9][C:6]2[CH:7]=[CH:8][C:3]([O:2][CH3:1])=[CH:4][CH:5]=2)=[O:17])=[CH:14][CH:13]=1)#[N:11]

参加物

反応物 2

HCID 7732P-Anisidine

HCID 120874-Cyanobenzoic acid

生成物 1

HCID 26650214-cyano-N-(4-methoxyphenyl)benzamide収率 91.7%

実験手順

Using p-anisidine (1.35 g, 11.0 mmol) and 4-cyanobenzoic acid (1.47 g, 10.0 mmol), the procedure of Reference Example 16 was repeated to obtain 2.31 g (91.7%) of the title compound in the form of colorless needle crystals.

出典と根拠

ORDレコード: ord-ac9b042f4b28460bbb5f5ac06fb31c97
出典データセット: uspto-grants-1998_03
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05728835

反応ノート

読み込み中…