Water → N-[2-(7-methoxy-1-naphthyl)ethyl]phthalimide

反応式

C1(S(O[CH2:11][CH2:12][C:13]2[C:22]3[C:17](=[CH:18][CH:19]=[C:20]([O:23][CH3:24])[CH:21]=3)[CH:16]=[CH:15][CH:14]=2)(=O)=O)C=CC=CC=1.[C:25]1(=[O:35])[NH:29][C:28](=[O:30])[C:27]2=[CH:31][CH:32]=[CH:33][CH:34]=[C:26]12.[K].O>CN(C)C=O>[CH3:24][O:23][C:20]1[CH:21]=[C:22]2[C:17]([CH:16]=[CH:15][CH:14]=[C:13]2[CH2:12][CH2:11][N:29]2[C:28](=[O:30])[C:27]3=[CH:31][CH:32]=[CH:33][CH:34]=[C:26]3[C:25]2=[O:35])=[CH:18][CH:19]=1

参加物

実験手順

The compound IV (14 g, 0.041 mol) produced as described above and potassium phthalimide (8.3 g, 0.045 mol) were added into a flask containing dimethylformamide (180 ml) as a solvent, heated and refluxed for 2 hours. After cooling the content to room temperature, 200 ml of water was added. The mixture was stirred and filtered. The filter cake formed was washed with water and dried, to produce 10.8 g of N-[2-(7-methoxy-1-naphthyl)ethyl]phthalimide (II). The yield was 80%. The melting point was 159-160° C.