2,2-dimethyl-3,4-dihydro-2H-1-benzopyran-6-carbaldehyde → 3-(2,2-Dimethylchroman-6-ylmethylene)-5-fluoro-1,3-dihydroindol-2-one

HRID 24376

反応式

HRID 24376 の反応式
[CH3:1][C:2]1([CH3:14])[CH2:11][CH2:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([CH:12]=O)[CH:8]=2)[O:3]1.[F:15][C:16]1[CH:17]=[C:18]2[C:22](=[CH:23][CH:24]=1)[NH:21][C:20](=[O:25])[CH2:19]2>>[CH3:1][C:2]1([CH3:14])[CH2:11][CH2:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([CH:12]=[C:19]3[C:18]4[C:22](=[CH:23][CH:24]=[C:16]([F:15])[CH:17]=4)[NH:21][C:20]3=[O:25])[CH:8]=2)[O:3]1

参加物

3

反応物 2

HCID 17977512,2-dimethyl-3,4-dihydro-2H-1-benzopyran-6-carbaldehydeHCID 37310125-fluoro-1,3-dihydro-2H-indol-2-one

生成物 1

HCID 544054613-(2,2-Dimethylchroman-6-ylmethylene)-5-fluoro-1,3-dihydroindol-2-one

実験手順

2,2-Dimethyl-6-formylchromane (commercially available) was condensed with 5-fluoro-2-oxindole to give 0.3 g of 3-(2,2-Dimethylchroman-6-ylmethylene)-5-fluoro-1,3-dihydroindol-2-one as a yellow-orange solid.

出典と根拠

ORDレコード
ord-7a06d2849b7a4e5bb350a97a0b22211f
出典データセット
uspto-grants-2005_02
特許番号
US06855730B2

関連ノート

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