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2-Bromo-4,5-dimethoxybenzoic acid → 5-Acetylamino-2-[1,2,3]triazol-2-yl-benzoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Bromo-4,5-dimethoxybenzoic acid | HCID 222963 | — |
| 反応物 | 5-Acetamido-2-bromobenzoic acid | HCID 2734159 | — |
| 反応物 | 6-Methyl-2-[1,2,3]triazol-2-yl-nicotinic acid | HCID 67086855 | — |
| 生成物 | 5-Acetylamino-2-[1,2,3]triazol-2-yl-benzoic acid | HCID 67116704 | — |
反応手順
The title compound was prepared in a manner analogous to Intermediate 70 substituting 5-acetamido-2-bromobenzoic acid for 2-bromo-4,5-dimethoxybenzoic acid. MS (ESI): mass calculated for C11H10N4O3, 246.22; m/z found 247.3 [M+H]+. 1H NMR (400 MHz, CD3OD): 8.09 (t, J=2.8 Hz, 1H), 7.92-7.86 (m, 3H), 7.66 (dd, J=8.7, 3.3 Hz, 1H), 2.17 (dd, J=2.5, 1.3 Hz, 3H).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08653263B2 |
| 出典データセット | uspto-grants-2014_02 |
| ORD ID | ord-46c87fffd8e24d7ca8fb268a1fdac41b |
| 出典メモ | uspto-grants-2014_02 |