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2-(Thiophen-2-yl)benzoic acid → 2-(4-Phenylpyrimidin-2-yl)-5-[(2-thiophen-2-ylphenyl)carbonyl]octahydro-pyrrolo[3,4-c]pyrrole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-(Thiophen-2-yl)benzoic acid | HCID 5105623 | — |
| 反応物 | 2-(4-Phenyl-pyrimidin-2-yl)-octahydro-pyrrolo[3,4-c]pyrrole | HCID 69939098 | — |
| 生成物 | 2-(4-Phenylpyrimidin-2-yl)-5-[(2-thiophen-2-ylphenyl)carbonyl]octahydro-pyrrolo[3,4-c]pyrrole | HCID 52916848 | — |
反応手順
The title compound was prepared in a manner analogous to Example 15 utilizing Intermediate 26 and 2-thiophen-2-yl-benzoic acid. MS (ESI) mass calcd. for C27H24N4OS, 452.58; m/z found, 453.2 [M+H]+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08653263B2 |
| 出典データセット | uspto-grants-2014_02 |
| ORD ID | ord-9a06263fe6a74814b68d1afd305622cd |
| 出典メモ | uspto-grants-2014_02 |