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HRID 243916作成日：2026年10月27日

2-(4-Fluorophenyl)benzoic acid → 2-{5-[(4'-Fluorobiphenyl-2-yl)carbonyl]hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}quinoxaline

https://huagongshe.com/reaction/243916

反応式

関与物質

役割名称HCID仕込み量
反応物2-(4-Fluorophenyl)benzoic acidHCID 2782687—
反応物2-(Hexahydro-pyrrolo[3,4-c]pyrrol-2-yl)-quinoxalineHCID 61037281—
生成物2-{5-[(4'-Fluorobiphenyl-2-yl)carbonyl]hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}quinoxalineHCID 52916933—

反応手順

The title compound was prepared in a manner analogous to Example 15 utilizing Intermediate 35 and 4′-fluoro-biphenyl-2-carboxylic acid. MS (ESI) mass calcd. for C27H23FN4O, 438.51; m/z found, 439.2 [M+H]+.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08653263B2
出典データセットuspto-grants-2014_02
ORD IDord-8ea1d7758f264052947b13ee3b075cd5
出典メモuspto-grants-2014_02