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HRID 243998作成日：2026年10月26日

4'-(Trifluoromethyl)(1,1'-biphenyl)-2-carboxylic acid → (5-Quinoxalin-2-yl-hexahydro-pyrrolo[3,4-c]pyrrol-2-yl)-(4'-trifluoromethyl-biphenyl-2-yl)-methanone

https://huagongshe.com/reaction/243998

反応式

関与物質

役割名称HCID仕込み量
反応物4'-(Trifluoromethyl)(1,1'-biphenyl)-2-carboxylic acidHCID 55251—
反応物2-(Hexahydro-pyrrolo[3,4-c]pyrrol-2-yl)-quinoxalineHCID 61037281—
生成物(5-Quinoxalin-2-yl-hexahydro-pyrrolo[3,4-c]pyrrol-2-yl)-(4'-trifluoromethyl-biphenyl-2-yl)-methanoneHCID 67116489—

反応手順

The title compound was prepared in a manner analogous to Example 15 utilizing Intermediate 35 and 4′-trifluoromethyl-biphenyl-2-carboxylic acid. MS (ESI): mass calculated for C28H23F3N4O, 488.50; m/z found 489.2 [M+H]+.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08653263B2
出典データセットuspto-grants-2014_02
ORD IDord-852d7d83eecb4d8cad3ec3a95baa068e
出典メモuspto-grants-2014_02