4-Methoxy-2-methylbenzoic acid → (4-Methoxy-2-methyl-phenyl)-(5-quinoxalin-2-yl-hexahydro-pyrrolo[3,4-c]pyrrol-2-yl)-methanone

HRID 244001

反応式

HRID 244001 の反応式
[CH2:1]1[CH:5]2[CH2:6][NH:7][CH2:8][CH:4]2[CH2:3][N:2]1[C:9]1[CH:18]=[N:17][C:16]2[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=2)[N:10]=1.[CH3:19][O:20][C:21]1[CH:29]=[CH:28][C:24]([C:25](O)=[O:26])=[C:23]([CH3:30])[CH:22]=1>>[CH3:19][O:20][C:21]1[CH:29]=[CH:28][C:24]([C:25]([N:7]2[CH2:8][CH:4]3[CH:5]([CH2:1][N:2]([C:9]4[CH:18]=[N:17][C:16]5[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=5)[N:10]=4)[CH2:3]3)[CH2:6]2)=[O:26])=[C:23]([CH3:30])[CH:22]=1

参加物

3

反応物 2

HCID 5972164-Methoxy-2-methylbenzoic acidHCID 610372812-(Hexahydro-pyrrolo[3,4-c]pyrrol-2-yl)-quinoxaline

生成物 1

HCID 67117182(4-Methoxy-2-methyl-phenyl)-(5-quinoxalin-2-yl-hexahydro-pyrrolo[3,4-c]pyrrol-2-yl)-methanone

実験手順

The title compound was prepared in a manner analogous to Example 15 utilizing Intermediate 35 and 4-methoxy-2-methyl-benzoic acid. MS (ESI): mass calculated for C23H24N4O2, 388.47; m/z found 389.2 [M+H]+.

出典と根拠

ORDレコード
ord-fa0d41c144e44958a39a31abb459841a
出典データセット
uspto-grants-2014_02
特許番号
US08653263B2

関連ノート

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