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HRID 24475作成日：2026年10月25日

N-methyl-2-oxoindoline-5-sulfonamide → 4-(3-dimethylaminopropyl)-2-methyl-5-(5-methylsulfamoyl-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-1H-pyrrole-3-carboxylic acid

https://huagongshe.com/reaction/24475

反応式

関与物質

役割名称HCID仕込み量
反応物N-methyl-2-oxoindoline-5-sulfonamideHCID 10176909—
反応物4-(3-dimethylaminopropyl)-5-formyl-2-methyl-1H-pyrrole-3-carboxylic acidHCID 22571074—
生成物4-(3-dimethylaminopropyl)-2-methyl-5-(5-methylsulfamoyl-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-1H-pyrrole-3-carboxylic acidHCID 5414950322.4%

反応手順

2-Oxo-2,3-dihydro-1H-indole-5-sulfonic acid methylamide (113 mg) was condensed with 4-(3-dimethylaminopropyl)-5-formyl-2-methyl-1H-pyrrole-3-carboxylic acid (119 mg) to give 50 mg 4-(3-dimethylaminopropyl)-2-methyl-5-(5-methylsulfamoyl-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-1H-pyrrole-3-carboxylic acid.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US06855730B2
出典データセットuspto-grants-2005_02
ORD IDord-9053dda97a26429d9d87388cdc5e7a24
出典メモuspto-grants-2005_02