Triphenylphosphine → N-Boc-Imino-(triphenyl)phosphorane

HRID 244927ノート

反応式

HRID 244927 の反応式
[C:1]([N:8]=[N+]=[N-])(=[O:7])[O:2][C:3]([CH3:6])([CH3:5])[CH3:4].[C:11]1([P:17]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>C(OCC)C>[C:24]1([P:17]([C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=2)([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[N:8][C:1]([O:2][C:3]([CH3:6])([CH3:5])[CH3:4])=[O:7])[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=1

参加物

4

反応物 2

HCID 11776TriphenylphosphineHCID 61256Carbonazidic acid, 1,1-dimethylethyl ester

生成物 1

HCID 2756802N-Boc-Imino-(triphenyl)phosphorane

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒

実験手順

To the solution of t-butyl carbonazidate in diethyl ether, 49.6 g (0.189 mol) of triphenylphosphine was added in small portions under cooling with ice, and the reaction solution was stirred at room temperature for 1 hour, and the precipitated solid was collected by filtration, washed with 200 mL of hexane and dried under reduced pressure to give 67 g of the desired product as white crystals.

後処理

  1. temperatureunder cooling with ice
  2. filtrationthe precipitated solid was collected by filtration
  3. washwashed with 200 mL of hexane
  4. customdried under reduced pressure

出典と根拠

ORDレコード
ord-05f3fdf7355f476b92d59ee2abcadbb6
出典データセット
uspto-grants-2014_02
特許番号
US08658686B2

反応ノート

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