Hydrochloric Acid → 1350712-71-8

HRID 246020ノート

反応式

HRID 246020 の反応式
[C:1]([C:3]([CH3:14])([CH3:13])[CH:4]([NH:6][S@@](C(C)(C)C)=O)[CH3:5])#[N:2].[ClH:15]>CO>[ClH:15].[NH2:6][C@@H:4]([CH3:5])[C:3]([CH3:14])([CH3:13])[C:1]#[N:2]

参加物

4

反応物 2

HCID 313Hydrochloric AcidHCID 86659449HCID 86659449、化合物

生成物 1

HCID 866594481350712-71-8収率 94%

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

(R)-2-Methyl-propane-2-sulfinic acid (2-cyano-1,2,2-trimethyl-ethyl)-amide (2.93 g, 13.6 mmol) was dissolved in MeOH and HCl (4.0 M in 1,4-dioxane, 6.8 mL, 27.2 mmol) was added. The reaction mixture was stirred at room temperature for 1 h then concentrated to give 1.90 g (94%) of (S)-3-amino-2,2-dimethyl-butyronitrile hydrochloride as a white solid which was used without further purification.

後処理

  1. concentrationthen concentrated

出典と根拠

ORDレコード
ord-2535e719abba47f1b3ce667ab8c1b679
出典データセット
uspto-grants-2014_02
特許番号
US08658646B2

反応ノート

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