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HRID 24613作成日：2026年10月23日
3,3-Diphenylpropylamine → Benzyl 4-(3-chlorophenyl)-3-(3,3-diphenylpropylcarbamoyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
https://huagongshe.com/ja/reaction/24613
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 3,3-Diphenylpropylamine | HCID 79698 | — |
| 反応物 | 5-benzyl 1-(4-nitrophenyl) 6-(3-chlorophenyl)-2-methoxy-4-methyl-6H-pyrimidine-1,5-dicarboxylate | HCID 69745932 | — |
| 溶媒 | Acetonitrile | HCID 6342 | — |
| 生成物 | Benzyl 4-(3-chlorophenyl)-3-(3,3-diphenylpropylcarbamoyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate | HCID 15546109 | — |
反応手順
10 ml of acetonitrile was added to a mixture of 200 mg (0.373 mmol) of 5-benzyl 1-(4-nitrophenyl) 6-(3-chlorophenyl)-2-methoxy-4-methyl-6H-pyrimidine-1,5-dicarboxylate and 78.9 mg (0.373 mmol) of 3,3-diphenylpropylamine, and they were stirred at 60° C. for 30 minutes. The solvent was evaporated under reduced pressure to obtain the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 特許番号 | US06855716B2 |
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| 出典データセット | uspto-grants-2005_02 |
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| ORD ID | ord-74147c16a95240d69ee024fbc23bdbd2 |
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| 出典メモ | uspto-grants-2005_02 |
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