Aluminum isopropoxide → HCID 20163297、化合物

反応式

CC([O-])C.CC([O-])C.CC([O-])C.[Al+3].[CH3:14][C:15]1([C:23](=[O:25])[CH3:24])[CH:20]([CH3:21])[CH2:19][C:18]([CH3:22])=[CH:17][CH2:16]1.C(O)(C)C.CC(C)=O>C(O)(C)C>[CH3:14][C:15]1([CH:23]([OH:25])[CH3:24])[CH:20]([CH3:21])[CH2:19][C:18]([CH3:22])=[CH:17][CH2:16]1

参加物

実験手順

A solution of 0.33 moles (68 g) aluminum isopropylate in 600 ml isopropanol was heated to boiling in a 1-liter 3-necked flask with a magnetic stirrer, packed column, dropping funnel and thermometer. Within two hours 1 mole (166 g) 1-(1,4,6-trimethylcyclohex-3-en-1-yl)ethan-1-one (as per Example 1) was added dropwise to the boiling solution, and at the same time the isopropanol/acetone mixture formed was distilled off. After 10 hours the reaction was ended (after no more acetone could be detected in the distillate). Thereupon isopropanol still remaining was drawn off, and 175 ml 20% by weight hydrochloric acid was added to the residue after cooling. Extraction was carried out and the organic phase was washed free of acid. After fractional distillation 151 g of the desired end product was obtained, corresponding to 90% of the theoretical amount.