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HRID 247143作成日：2026年10月26日
1,4-Naphthoquinone → 1,4,4a,9a-tetrahydro-1-[(2,3,6-trideoxy-4-O-p-nitrobenzoyl-3-trifluoroacetamido-alpha-L-lyxo-hexo-pyranosyl)methyl]-anthracene-9,10-dione
https://huagongshe.com/reaction/247143
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 1,4-Naphthoquinone | HCID 8530 | — |
| 反応物 | (E)-1-(2,3,6-trideoxy-4-O-p-nitrobenzoyl-3-trifluoroacetamido-alpha-L-lyxo-hexopyranosyl)-2,4-pentadiene | HCID 86741864 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | 1,4,4a,9a-tetrahydro-1-[(2,3,6-trideoxy-4-O-p-nitrobenzoyl-3-trifluoroacetamido-alpha-L-lyxo-hexo-pyranosyl)methyl]-anthracene-9,10-dione | HCID 86741863 | 65.4% |
反応手順
Ninety mg (0.203 mmoles) of (E)-1-(2,3,6-trideoxy-4-O-p-nitrobenzoyl-3-trifluoroacetamido-α-L-lyxo-hexopyranosyl)-2,4-pentadiene and 22.0 mg (0.140 mmoles) of 1,4 naphthoquinone were mixed in 10 ml toluene and the mixture was heated under N2 at 80°-88° C. for 4 hr. The reaction was chilled to 0° C. and filtered to give 55 mg (65%) 1,4,4a,9a-tetrahydro-1-[(2,3,6-trideoxy-4-O-p-nitrobenzoyl-3-trifluoroacetamido-α-L-lyxo-hexo-pyranosyl)methyl]-anthracene-9,10-dione in impure form.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 特許番号 | US04705850 |
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| 出典データセット | uspto-grants-1987_11 |
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| ORD ID | ord-98dcba6dc26745f0a09eb5fa0e55e70b |
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| 出典メモ | uspto-grants-1987_11 |
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