Acetic Anhydride → (3-chlorophenyl)methyl Acetate

HRID 247727

反応式

HRID 247727 の反応式
[Cl:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][CH:9]=1)[CH2:5][OH:6].[C:10](OC(=O)C)(=[O:12])[CH3:11]>C1C=CC=CC=1>[C:10]([O:6][CH2:5][C:4]1[CH:7]=[CH:8][CH:9]=[C:2]([Cl:1])[CH:3]=1)(=[O:12])[CH3:11]

参加物

4

反応物 2

HCID 7918Acetic AnhydrideHCID 701173-Chlorobenzyl alcohol

生成物 1

HCID 11217649(3-chlorophenyl)methyl Acetate収率 96%

試薬・触媒・溶媒 1

HCID 241Benzene溶媒

実験手順

Into a solution of 84.4 g. (0.592 mole) of 3-chlorobenzyl alcohol in 40 cm3. of benzene 61.5 g. (0.6 mole) of acetic acid anhydride are dropped during 15 minutes while boiling. The reaction mixture is refluxed with 100 cm3. of benzene and washed with 100 cm3. of water thoroughly. The organic phase is separated and evaporated. 105.2 g. of 3-chlorobenzyl acetate are obtained which is suitable to ether-formation. nD20 : 1.5226, yield 96%.

後処理

  1. temperatureThe reaction mixture is refluxed with 100 cm3
  2. washof benzene and washed with 100 cm3
  3. customThe organic phase is separated
  4. customevaporated

出典と根拠

ORDレコード
ord-0454e46b42c644bf8206535480ccf04b
出典データセット
uspto-grants-1987_11
特許番号
US04709081

関連ノート

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