Ethyl diazoacetate → Ethyl chrysanthemate

HRID 247732

反応式

HRID 247732 の反応式
[CH3:1][C:2](=[CH:4][CH:5]=[C:6]([CH3:8])[CH3:7])[CH3:3].[N+](=[CH:11][C:12]([O:14][CH2:15][CH3:16])=[O:13])=[N-]>C(Cl)Cl>[CH3:16][CH2:15][O:14][C:12]([CH:11]1[C:6]([CH3:8])([CH3:7])[CH:5]1[CH:4]=[C:2]([CH3:3])[CH3:1])=[O:13]

参加物

4

反応物 2

HCID 12192Ethyl diazoacetateHCID 12992Biisocrotyl

生成物 1

HCID 7334Ethyl chrysanthemate収率 89.6%

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒2 回

実験手順

A flask was charged with CH2Cl2 (25 mL), 2,5-dimethyl-2,4-hexadiene (25 mL) and 0.45 g of the Cu,K-PFIEP[SO3H] catalyst, prepared as described above. A solution of ethyl diazoacetate (2.5 g) in CH2Cl2 (25 mL) was added slowly dropwise and the resulting reaction mixture was stirred for 24 hours at ambient temperature. Gas chromatography analysis showed that the resulting product contained cis- and trans-ethyl chrysanthemumates in a 1:1.66 isomer ratio and a combined yield of 89.6%.

後処理

  1. customprepared
  2. customthe resulting reaction mixture

出典と根拠

ORDレコード
ord-5b3398a32e804dbd8c4f7bb4716c2929
出典データセット
uspto-grants-1987_11
特許番号
US04709085

関連ノート

読み込み中…