4-Hydroxybenzoic Acid → Benzoic acid, 4-((1-oxodecyl)oxy)-

HRID 247784

反応式

HRID 247784 の反応式
[OH:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][CH:3]=1.C(N(CC)CC)C.[C:18](Cl)(=[O:28])[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27].Cl>ClCCl.CN(C1C=CC=CN=1)C>[C:18]([O:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][CH:3]=1)(=[O:28])[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27]

参加物

7

反応物 4

HCID 1354-Hydroxybenzoic AcidHCID 313Hydrochloric AcidHCID 8471TriethylamineHCID 66982Decanoyl chloride

生成物 1

HCID 3608562Benzoic acid, 4-((1-oxodecyl)oxy)-収率 78.7%

試薬・触媒・溶媒 2

HCID 218852-Dimethylaminopyridine触媒HCID 6344Dichloromethane溶媒

実験手順

To a solution of p-hydroxybenzoic acid (3 g) and triethylamine (2.4 g) in dichloromethane (30 ml) were added decanoyl chloride (4.3 g) and dimethylaminopyridine (0.2 g). The mixture was stirred at room temperature for about 20 hours. After dilute aqueous hydrochloric acid solution was added to the mixture, an organic layer was separated by a funnel. After the solution was distilled to remove the solvent, the residue was washed with n-hexane and dried to obtain the titled compound (about 5 g).

後処理

  1. customan organic layer was separated by a funnel
  2. distillationAfter the solution was distilled
  3. customto remove the solvent
  4. washthe residue was washed with n-hexane
  5. customdried

出典と根拠

ORDレコード
ord-d0f29f1ace974ea1bd0bc63aa6f31766
出典データセット
uspto-grants-1993_05
特許番号
US05207947

関連ノート

読み込み中…