Hydrochloric Acid → HCID 11780934、化合物

HRID 247845ノート

反応式

HRID 247845 の反応式
[CH3:1][N:2]([CH:6]1[CH2:11][CH2:10][N:9]([CH2:12][CH2:13][CH2:14][CH2:15][O:16][C:17]2[CH:22]=[CH:21][C:20]([F:23])=[CH:19][CH:18]=2)[CH2:8][CH2:7]1)C(=O)C.Cl>CO>[F:23][C:20]1[CH:19]=[CH:18][C:17]([O:16][CH2:15][CH2:14][CH2:13][CH2:12][N:9]2[CH2:8][CH2:7][CH:6]([NH:2][CH3:1])[CH2:11][CH2:10]2)=[CH:22][CH:21]=1

参加物

4

反応物 2

HCID 313Hydrochloric AcidHCID 19764643N-Methyl-N-{1-[4-(p-fluorophenoxy)butyl]-4-piperidyl}acetamide

生成物 1

HCID 11780934HCID 11780934、化合物

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

0.05 mole of the compound obtained in stage D is refluxed for 12 hours in the presence of 570 cm3 of methanol and 340 cm3 of 5N hydrochloric acid. The methanol is evaporated and the mixture is poured into ice and then basified with sodium hydroxide. It is extracted with ether.

後処理

  1. customThe methanol is evaporated
  2. additionthe mixture is poured into ice
  3. extractionIt is extracted with ether

出典と根拠

ORDレコード
ord-c01548b052cb476bb7336025740cb417
出典データセット
uspto-grants-1993_05
特許番号
US05208243

反応ノート

読み込み中…