関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Imidazole | HCID 795 | — |
| 反応物 | Ethyl orthoformate | HCID 31214 | — |
| 触媒 | p-Toluenesulfonic acid | HCID 6101 | — |
| 生成物 | 1-(diethoxymethyl)-1H-imidazole | HCID 3849535 | 72.4% |
反応手順
Imidazole (6.81 g, 0.10 mol, 1.0 eq), triethyl orthoformate (66.5 mL, 0.40 mol, 4.0 eq) and para-toluenesulfonic acid (0.5 g) were combined and heated at 130° C. Ethanol was slowly distilled off. After the distillation of the ethanol ceased, the reaction was distilled using a floor pump (0.1 mm). Excess triethyl orthoformate distilled at 50° C. and then the product was distilled at 78°-84° C. to give the title compound (12.316 g, 72%). B. 2-Butyl-1H-imidazole
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05208235 |
|---|
| 出典データセット | uspto-grants-1993_05 |
|---|
| ORD ID | ord-06b1da150e4241318a794b79309b0d3b |
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| 出典メモ | uspto-grants-1993_05 |
|---|
