化工社化工社 化学情報印刷レポート · 研究参考用
Ammonium nitrate → 1-Acetyl-5-nitroindolin-2-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ammonium nitrate | HCID 22985 | — |
| 反応物 | 1-Acetylindolin-2-one | HCID 323719 | — |
| 溶媒 | Sulfuric Acid | HCID 1118 | — |
| 生成物 | 1-Acetyl-5-nitroindolin-2-one | HCID 2839329 | — |
反応手順
17.5 g (0.10 mol) of 1-acetyl-2-indolinone are dissolved in 100 ml of conc. sulphuric acid and at −10° C. 8.8 g (0.11 mol) of ammonium nitrate are added batchwise and stirred for 15 minutes. The reaction is poured onto ice water, suction filtered and washed with water. The residue is distributed in ethyl acetate/water, the combined organic extracts are dried and concentrated by evaporation.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06855710B2 |
| 出典データセット | uspto-grants-2005_02 |
| ORD ID | ord-876a4116b49845fd9885779f56dd4f70 |
| 出典メモ | uspto-grants-2005_02 |