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Myristyl bromide → 3,4-Bis(tetradecyloxy)benzoic acid methyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Myristyl bromide | HCID 8208 | — |
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | Methyl 3,4-Dihydroxybenzoate | HCID 287064 | — |
| 触媒 | Potassium Iodide | HCID 4875 | — |
| 溶媒 | Methyl Ethyl Ketone | HCID 6569 | — |
| 生成物 | 3,4-Bis(tetradecyloxy)benzoic acid methyl ester | HCID 12048557 | 98.6% |
反応手順
A mixture of 15.0 g of product from Example 102, 53.2 g of 1-bromotetradecane, 37 g of potassium carbonate, 1.04 g of potassium iodide and 350 ml of 2-butanone is heated at reflux for 28.5 hours. The reaction is cooled to room temperature, filtered and the filtrate concentrated in vacuo. The residue is recrystallized from methylene chloride/hexane to give 49.33 g of the desired product.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05208247 |
| 出典データセット | uspto-grants-1993_05 |
| ORD ID | ord-1c278a233c4c4e89bb4e6d6464fbe472 |
| 出典メモ | uspto-grants-1993_05 |