化工社化工社 化学情報印刷レポート · 研究参考用
1-Naphthol → (2R)-1-(butyryloxy)-3-(1-naphthyloxy)-2-propanol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-Naphthol | HCID 7005 | — |
| 反応物 | (2R)-Oxiran-2-ylmethyl butanoate | HCID 2724536 | — |
| 触媒 | Tetrabutylammonium Iodide | HCID 67553 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | (2R)-1-(butyryloxy)-3-(1-naphthyloxy)-2-propanol | HCID 53988552 | 75% |
反応手順
To a solution of 144 g (1 mol) of 1-naphthol and 7.4 g (0.02 mol) of tetrabutylammonium iodide in 200 ml of toluene was added 144 g (1 mol) of (R)-glycidyl butyrate over a period of 15 min at a temperature of 120° C., and the mixture was kept at this temperature for a further 4 h. Conventional subsequent treatment of the reaction mixture gave the required compound as an oil, yield about 75%.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05208333 |
| 出典データセット | uspto-grants-1993_05 |
| ORD ID | ord-86e317ef3b474747a22b6fcc78057d05 |
| 出典メモ | uspto-grants-1993_05 |