1-Bromohexane → HCID 54034378、化合物

HRID 248352ノート

反応式

HRID 248352 の反応式
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6](/[CH:9]=[C:10](\[N+:22]#[C-:23])/[C:11](/[N+:20]#[C-:21])=[CH:12]/[C:13]2[CH:18]=[CH:17][C:16]([OH:19])=[CH:15][CH:14]=2)=[CH:5][CH:4]=1.C(=O)([O-])[O-].[K+].[K+].[CH2:30](Br)[CH2:31][CH2:32][CH2:33][CH2:34][CH3:35]>CN(C=O)C>[CH2:30]([O:19][C:16]1[CH:17]=[CH:18][C:13]([CH:12]=[C:11]([N+:20]#[C-:21])[C:10]([N+:22]#[C-:23])=[CH:9][C:6]2[CH:5]=[CH:4][C:3]([O:2][CH3:1])=[CH:8][CH:7]=2)=[CH:14][CH:15]=1)[CH2:31][CH2:32][CH2:33][CH2:34][CH3:35]

参加物

5

反応物 3

HCID 81011-BromohexaneHCID 11430Potassium CarbonateHCID 6441021xanthocillin X monomethyl ether

生成物 1

HCID 54034378HCID 54034378、化合物収率 94%

試薬・触媒・溶媒 1

HCID 6228Dimethylformamide溶媒

実験手順

13 mg of xanthocillin X monomethyl ether was dissolved in 2 ml of DMF and 40 mg of potassium carbonate was added thereto. Further, 50 μl of n-hexyl bromide was added thereto and the mixture thus formed was extracted with 30 ml portions of ethyl acetate thrice. The extracts were combined, successively washed with water and a saturated aqueous solution of sodium chloride and dried over sodium sulfate. The sodium sulfate was filtered off and the solvent was distilled from the filtrate. Thus 15 mg of 1-(4'-n-hexyloxyphenyl)-4-(4'-methoxyphenyl)-2,3-diisocyano-1,3-butadiene was obtained in the form of a brown solid. Yield: 94%.

後処理

  1. customthe mixture thus formed
  2. extractionwas extracted with 30 ml portions of ethyl acetate thrice
  3. washsuccessively washed with water
  4. dry with materiala saturated aqueous solution of sodium chloride and dried over sodium sulfate
  5. filtrationThe sodium sulfate was filtered off
  6. distillationthe solvent was distilled from the filtrate

出典と根拠

ORDレコード
ord-7ae9a2fe3d7d477693aba126e9f970dd
出典データセット
uspto-grants-1993_05
特許番号
US05210097

反応ノート

読み込み中…