Carbon Dioxide → S-(alpha,beta-dicarboxyethyl)glutathione calcium

HRID 248802

反応式

HRID 248802 の反応式
[C:1]([CH:4]([S:9][CH2:10][C@@H:11]([C:22]([NH:24][CH2:25][C:26]([OH:28])=[O:27])=[O:23])[NH:12][C:13](=[O:21])[CH2:14][CH2:15][C@@H:16]([C:18]([OH:20])=[O:19])[NH2:17])[CH2:5][C:6]([OH:8])=[O:7])([OH:3])=[O:2].C(=O)([O-])[O-].[Ca+2:33].C(=O)=O>O>[Ca:33].[C:1]([CH:4]([S:9][CH2:10][C@@H:11]([C:22]([NH:24][CH2:25][C:26]([OH:28])=[O:27])=[O:23])[NH:12][C:13](=[O:21])[CH2:14][CH2:15][C@@H:16]([C:18]([OH:20])=[O:19])[NH2:17])[CH2:5][C:6]([OH:8])=[O:7])([OH:3])=[O:2]

参加物

5

反応物 3

HCID 280Carbon DioxideHCID 10112Calcium CarbonateHCID 9802383S-(1,2-Dicarboxyethyl)glutathione

生成物 1

HCID 86746843S-(alpha,beta-dicarboxyethyl)glutathione calcium収率 100.5%

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

In 40 ml of water is dissolved 2 g of S-(α,β-dicarboxyethyl)glutathione followed by addition of 1 g of calcium carbonate. The mixture is stirred under warming. When the evolution of carbon dioxide gas has ceased, the excess of calcium carbonate is filtered off and the filtrate is concentrated under reduced pressure. To the concentrate is added ethanol and the resulting white crystals are collected by filtration and recrystallized from water-ethanol. Thus is obtained 2.2 g of the title compound as white powdery crystals.

後処理

  1. temperatureunder warming
  2. filtrationthe excess of calcium carbonate is filtered off
  3. concentrationthe filtrate is concentrated under reduced pressure
  4. additionTo the concentrate is added ethanol
  5. filtrationthe resulting white crystals are collected by filtration
  6. customrecrystallized from water-ethanol

出典と根拠

ORDレコード
ord-c2f5fdbeaf194800bb9fed483cfb3468
出典データセット
uspto-grants-1993_05
特許番号
US05212159

関連ノート

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