関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | 4,4'-Dichlorobenzophenone | HCID 7034 | — |
| 反応物 | Sodium borohydride | HCID 4311764 | — |
| 溶媒 | Isopropanol | HCID 3776 | — |
| 生成物 | 4,4'-Dichlorobenzhydrol | HCID 7033 | 98.8% |
反応手順
To a solution of 4,4'-dichlorobenzophenone (2.51 g) in isopropyl alcohol (15 ml) was added sodium borohydride (0.45 g). The mixture was stirred for 4 hours at 50° C. and poured into diluted hydrochloric acid (60 ml). The organic layer was extracted with ethyl acetate (20 ml) and washed with water (30 ml×2). The solution was dried over magnesium sulfate. The solvent was removed in vacuo to give colorless oil of bis(4-chlorophenyl)methanol (2.50 g).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05212320 |
|---|
| 出典データセット | uspto-grants-1993_05 |
|---|
| ORD ID | ord-1992318223c54782a559e8236f189c69 |
|---|
| 出典メモ | uspto-grants-1993_05 |
|---|
