関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | DL-Arabinose | HCID 854 | — |
| 反応物 | L-Lysine | HCID 5962 | — |
| 反応物 | Aldehydo-D-ribose | HCID 5311110 | — |
| 反応物 | HCID 178418600 | HCID 178418600 | — |
| 生成物 | Pentosidine | HCID 119593 | — |
反応手順
In order to confirm the pentose-derived nature of the native fluorophore 100 mM each of L-lysine, L-arginine and D-ribose were heated for 1 hour at 80° C. Injection of a small amount of this synthetic material on HPLC revealed a major fluorescent peak co-eluting with the native fluorophore. (see FIG. 5) In order to substantiate the proposed structure, the synthetic fluorophore was prepared preparatively and purified. Total yield was 21 mg; i.e., 0.02% of the reactants.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 特許番号 | US05214138 |
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| 出典データセット | uspto-grants-1993_05 |
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| ORD ID | ord-bffb7174a0ac4af9a4dc20f013edb573 |
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| 出典メモ | uspto-grants-1993_05 |
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