2-Chloro-5-chloromethylthiazole → 1-(2-Chloro-1,3-thiazol-5-yl)-N-methylmethanamine

HRID 249500

反応式

HRID 249500 の反応式
[Cl:1][C:2]1[S:3][C:4]([CH2:7]Cl)=[CH:5][N:6]=1.Cl[C:10]1C(CCl)=CC=C(Cl)[N:11]=1>C(Cl)Cl>[Cl:1][C:2]1[S:3][C:4]([CH2:7][NH:11][CH3:10])=[CH:5][N:6]=1

参加物

4

反応物 2

HCID 27631792-Chloro-5-chloromethylthiazoleHCID 6451791Pyridine, 2,6-dichloro-3-(chloromethyl)-

生成物 1

HCID 224503721-(2-Chloro-1,3-thiazol-5-yl)-N-methylmethanamine

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

The reaction procedure of Reference Example 11 was repeated except that crude 2-chloro-5-chloromethylthiazole was used in lieu of 2,6-dichloro-3-pyridylmethyl chloride and that CH2Cl2 was used as the extractant. The procedure gave the title compound as a crude oil.

後処理

  1. customThe reaction procedure of Reference Example 11

出典と根拠

ORDレコード
ord-1c896f94bd174fccafd162e552160224
出典データセット
uspto-grants-1993_05
特許番号
US05214152

関連ノート

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