(2,6-Dichloropyridin-3-YL)methanamine → 1-(2,6-Dichloro-3-pyridylmethyl)amino-1-methylamino-2-nitroethylene
反応式
[Cl:1][C:2]1[C:7]([CH2:8][NH2:9])=[CH:6][CH:5]=[C:4]([Cl:10])[N:3]=1.[CH3:11][NH:12][CH:13](SC)[CH2:14][N+:15]([O-:17])=[O:16]>CCO>[Cl:1][C:2]1[C:7]([CH2:8][NH:9][C:13]([NH:12][CH3:11])=[CH:14][N+:15]([O-:17])=[O:16])=[CH:6][CH:5]=[C:4]([Cl:10])[N:3]=1参加物
4
実験手順
A mixture of 1.2 g (0.007 mole) of (2,6dichloro-3-pyridylmethyl)amine and 1 g (0.007 mole) of 1-methylamino-1-methylthio-2-nitroethane was refluxed in 50 ml of EtOH for 6 hours. After cooling, the reaction mixture was concentrated and the resulting crystals were collected by filtration, washed with CH2Cl2 and a small amount of EtOH in that order and dried. The procedure gave 0.53 g of the title compound as a white powder.
後処理
- temperatureAfter cooling
- concentrationthe reaction mixture was concentrated
- filtrationthe resulting crystals were collected by filtration
- washwashed with CH2Cl2
- dry with materiala small amount of EtOH in that order and dried
出典と根拠
- ORDレコード
- ord-a8e6b8a12d474ac785b99ef3e44d02a6
- 出典データセット
- uspto-grants-1993_05
- 特許番号
- US05214152
反応ノート
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