(2,6-Dichloropyridin-3-YL)methanamine → S-methyl-N-ethyl-N-(6-fluoro-3-pyridylmethyl)-N'-methylisothiourea
反応式
Cl[C:2]1C(CN)=CC=C(Cl)N=1.[CH2:11]([N:13]([CH2:18][C:19]1[CH:20]=[N:21][C:22]([F:25])=[CH:23][CH:24]=1)[C:14]([NH:16][CH3:17])=[S:15])[CH3:12].CNC(N(CC)CC1C=NC=CC=1)=S>>[CH3:2][S:15][C:14](=[N:16][CH3:17])[N:13]([CH2:11][CH3:12])[CH2:18][C:19]1[CH:20]=[N:21][C:22]([F:25])=[CH:23][CH:24]=1参加物
4
実験手順
The reaction procedure of Example 13 (2) was repeated except that N-ethyl-N-(6-fluoro-3-pyridylmethyl)-N'-methylthiourea was used in lieu of N-methyl-N'-ethyl-N'-(3-pyridylmethyl)thiourea to give S-methyl-N-ethyl-N-(6-fluoro-3-pyridylmethyl)-N'-methylisothiourea as a pale brown oil.
出典と根拠
- ORDレコード
- ord-be2cbbd117be4690ae99b4ff07cffda4
- 出典データセット
- uspto-grants-1993_05
- 特許番号
- US05214152
反応ノート
読み込み中…