化工社化工社 化学情報印刷レポート · 研究参考用
2-(4-Nitrophenyl)butyric acid → 2-(4-Aminophenyl)butanoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-(4-Nitrophenyl)butyric acid | HCID 24047 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 2-(4-Aminophenyl)butanoic acid | HCID 34655 | 92% |
反応手順
A solution of 2-(4'-nitrophenyl)butyric acid (6.99 g, 33.4 mmol) in 250 mL of EtOH and 0.5 g of 10% Pd-C was hydrogenated overnight at 55 psi. The solution was filtered and evaporated under vacuum to give 5.50 g (92%) of the desired product.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05214191 |
| 出典データセット | uspto-grants-1993_05 |
| ORD ID | ord-a9c1d3d2d2a743a29e28daf310be9010 |
| 出典メモ | uspto-grants-1993_05 |