Trifluoroacetohydrazide → HCID 178446280、化合物

HRID 249783ノート

反応式

HRID 249783 の反応式
[CH2:1]([NH:6][C:7]1[N:8]=[CH:9][NH:10][C:11]=1[C:12](SC)=[NH:13])[CH2:2][CH2:3][CH2:4][CH3:5].[F:16][C:17]([F:23])([F:22])[C:18]([NH:20][NH2:21])=O>C(O)C>[CH2:1]([NH:6][C:7]1[N:8]=[CH:9][NH:10][C:11]=1[C:12]1[NH:21][N:20]=[C:18]([C:17]([F:23])([F:22])[F:16])[N:13]=1)[CH2:2][CH2:3][CH2:4][CH3:5]

参加物

4

反応物 2

HCID 229753TrifluoroacetohydrazideHCID 135984704methyl 4-(pentylamino)-1H-imidazole-5-carbimidothioate

生成物 1

HCID 178446280HCID 178446280、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

The mixture of methyl 4-(pentylamino)-1H-imidazole-5-carbimidothioate (0.53 g, 2.4 mmol) and trifluoroacetic acid hydrazide (0.45 g, 3.5 mmol) in ethanol (10 mL) was refluxed overnight. The reaction mixture was concentrated to yield the product as slightly green viscous oil. LCMS calculated for C11H16F3N6(M+H): 289.1. found: 289.1.

後処理

  1. temperaturewas refluxed overnight
  2. concentrationThe reaction mixture was concentrated
  3. customto yield the product as slightly green viscous oil

出典と根拠

ORDレコード
ord-ae3d46556d5a4d618146d09e700d6d6f
出典データセット
uspto-grants-2011_01
特許番号
US07863285B2

反応ノート

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