戻る
化工社化工社 化学情報印刷レポート · 研究参考用
HRID 249832作成日：2026年10月26日

(3S)-1-azabicyclo[2.2.2]octan-3-amine dihydrochloride → (S)-N-(quinuclidine-8-yl)-2-(dimethylamino)benzoxazole-4-carboxamide

https://huagongshe.com/reaction/249832

反応式

関与物質

役割名称HCID仕込み量
反応物(3S)-1-azabicyclo[2.2.2]octan-3-amine dihydrochlorideHCID 12494973—
反応物2-(Dimethylamino)-1,3-benzoxazole-4-carboxylic acidHCID 66874030—
生成物(S)-N-(quinuclidine-8-yl)-2-(dimethylamino)benzoxazole-4-carboxamideHCID 52946744—

反応手順

Following general procedure GP-C1, a mixture of 2-(dimethylamino)benzoxazole-4-carboxylic acid and (S)-(−)-3-aminoquinuclidine dihydrochloride were coupled to provide (S)—N-(quinuclidine-8-yl)-2-(dimethylamino)benzoxazole-4-carboxamide, which was converted to the hydrochloride salt following general procedure GP-D1. 1H NMR and MS consistent.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07863271B2
出典データセットuspto-grants-2011_01
ORD IDord-25992f7a45df4c36ba766e2f2ff23c76
出典メモuspto-grants-2011_01