Citraconic Anhydrides → 3-BroMo-4-Methylfuran-2,5-dione

HRID 249990

反応式

HRID 249990 の反応式
[CH3:1][C:2]1[C:3](=[O:8])[O:4][C:5](=[O:7])[CH:6]=1.[Al](Br)(Br)[Br:10].BrBr>C(OCC)(=O)C>[Br:10][C:6]1[C:5](=[O:7])[O:4][C:3](=[O:8])[C:2]=1[CH3:1]

参加物

5

反応物 3

HCID 12012Citraconic AnhydridesHCID 24408BromineHCID 24409Aluminum bromide

生成物 1

HCID 105838543-BroMo-4-Methylfuran-2,5-dione収率 9,023.2%

試薬・触媒・溶媒 1

HCID 8857Ethyl Acetate溶媒

反応条件

温度
120 °C

実験手順

A mixture of 3-methyl-2,5-furandione (citraconic anhydride, 1 g), AlBr3 (26 mg) and Br2 (0.46 mL) was heated at 120° C. overnight. Ethyl acetate was then added and the organic phase was washed with HCl 0.1% and then with brine. The organic phase was dried and concentrated in vacuo to give the crude product (1.680 g) that was used without further purification.

後処理

  1. washthe organic phase was washed with HCl 0.1%
  2. customThe organic phase was dried
  3. concentrationconcentrated in vacuo

出典と根拠

ORDレコード
ord-7740d3fce82847729128eaba9969fa7f
出典データセット
uspto-grants-2011_01
特許番号
US07863299B2

関連ノート

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