methyl 6-bromo-1H-indole-2-carboxylate → Methyl 6-bromo-1-methyl-1H-indole-2-carboxylate

反応式

COC([C:5]1[C:13]2[C:8](=[CH:9][C:10]([Br:14])=[CH:11][CH:12]=2)[N:7]([CH3:15])[CH:6]=1)=O.[CH3:16][O:17][C:18](C1NC2C(C=1)=CC=C(Br)C=2)=[O:19]>>[CH3:16][O:17][C:18]([C:6]1[N:7]([CH3:15])[C:8]2[C:13]([CH:5]=1)=[CH:12][CH:11]=[C:10]([Br:14])[CH:9]=2)=[O:19]

参加物

反応物 2

HCID 754141methyl 6-bromo-1H-indole-2-carboxylate

HCID 57443279Methyl 6-bromo-1-methyl-1H-indole-3-carboxylate

生成物 1

HCID 4777911Methyl 6-bromo-1-methyl-1H-indole-2-carboxylate

実験手順

The title compound is prepared essentially as described in the preparation of 6-bromo-1-methyl-1H-indole-3-carboxylic acid methyl ester utilizing 6-bromo-1H-indole-2-carboxylic acid methyl ester, ES/MS m/e 270.0 (M+2).

出典と根拠

ORDレコード: ord-75ad529d079949c6961423e0739f8c78
出典データセット: uspto-grants-2011_01
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07863302B2

反応ノート

読み込み中…