Triethylamine → Ethyl 4-(3-(2,6-dimethylbenzyloxy)phenyl)-3-butenoate

HRID 25035ノート

反応式

HRID 25035 の反応式
C(N(CC)CC)C.[CH3:8][C:9]1[CH:31]=[CH:30][CH:29]=[C:28]([CH3:32])[C:10]=1[CH2:11][O:12][C:13]1[CH:14]=[C:15]([CH:19](Br)[CH2:20][CH2:21][C:22]([O:24][CH2:25][CH3:26])=[O:23])[CH:16]=[CH:17][CH:18]=1>C(Cl)(Cl)(Cl)Cl>[CH3:32][C:28]1[CH:29]=[CH:30][CH:31]=[C:9]([CH3:8])[C:10]=1[CH2:11][O:12][C:13]1[CH:14]=[C:15]([CH:19]=[CH:20][CH2:21][C:22]([O:24][CH2:25][CH3:26])=[O:23])[CH:16]=[CH:17][CH:18]=1

参加物

4

反応物 2

HCID 8471TriethylamineHCID 21964551Ethyl 4-(3-(2,6-dimethylbenzyloxy)phenyl)-4-bromobutyrate

生成物 1

HCID 67274119Ethyl 4-(3-(2,6-dimethylbenzyloxy)phenyl)-3-butenoate

試薬・触媒・溶媒 1

HCID 5943Carbon Tetrachloride溶媒

実験手順

Add Triethylamine to a solution of Ethyl 4-(3-(2,6-dimethylbenzyloxy)phenyl)-4-bromobutyrate (Step E) in carbon tetrachloride. After stirring approximately for 4 hours, the mixture can be filtered through a pad of silica gel few times, and concentrate to give the title compound.

後処理

  1. filtrationthe mixture can be filtered through a pad of silica gel few times
  2. concentrationconcentrate

出典と根拠

ORDレコード
ord-498751129cd4437dbc650b66414989b5
出典データセット
uspto-grants-2005_02
特許番号
US06858602B2

反応ノート

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