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3-Methylpyridine-2-carboxaldehyde → Bis-(3-methyl-pyridin-2-ylmethyl)-amine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-Methylpyridine-2-carboxaldehyde | HCID 1501874 | — |
| 反応物 | (3-Methylpyridin-2-yl)methanamine | HCID 1514370 | — |
| 反応物 | Sodium triacetoxyborohydride | HCID 5049666 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | Bis-(3-methyl-pyridin-2-ylmethyl)-amine | HCID 45098010 | — |
反応手順
Using General Procedure B: Reaction of 3-methyl-2-aminomethylpyridine and 3-methyl-2-pyridinecarboxaldehyde in CH2Cl2 with NaBH(OAc)3 gave bis-(3-methyl-pyridin-2-ylmethyl)-amine as a yellow oil. 1H NMR (CDCl3) δ 2.33 s, 6H), 4.06 (s, 4H), 7.08 (dd, 2H, J=9, 6 Hz), 7.42 (dd, 2H, J=9, 3 Hz), 8.41 (d, 2H, J=3 Hz).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07863293B2 |
| 出典データセット | uspto-grants-2011_01 |
| ORD ID | ord-3c63327a6cd144c2a461ba8a471ee995 |
| 出典メモ | uspto-grants-2011_01 |