Sodium triacetoxyborohydride → 4-((5-Chloro-3-methyl-pyridin-2-ylmethyl)-{3-[1-(4-fluoro-phenyl)-1-methyl-ethyl]-pyridin-2-ylmethyl}-amino)-piperidine-1-carboxylic acid tert-butyl ester

反応式

[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([C:11]2[C:12]([CH:17]=O)=[N:13][CH:14]=[CH:15][CH:16]=2)([CH3:10])[CH3:9])=[CH:4][CH:3]=1.[C:19]([O:23][C:24]([N:26]1[CH2:31][CH2:30][CH:29]([NH:32][CH2:33][C:34]2[C:39]([CH3:40])=[CH:38][C:37]([Cl:41])=[CH:36][N:35]=2)[CH2:28][CH2:27]1)=[O:25])([CH3:22])([CH3:21])[CH3:20].[BH-](OC(C)=O)(OC(C)=O)OC(C)=O.[Na+]>C(Cl)Cl>[C:19]([O:23][C:24]([N:26]1[CH2:27][CH2:28][CH:29]([N:32]([CH2:33][C:34]2[C:39]([CH3:40])=[CH:38][C:37]([Cl:41])=[CH:36][N:35]=2)[CH2:17][C:12]2[C:11]([C:8]([C:5]3[CH:4]=[CH:3][C:2]([F:1])=[CH:7][CH:6]=3)([CH3:9])[CH3:10])=[CH:16][CH:15]=[CH:14][N:13]=2)[CH2:30][CH2:31]1)=[O:25])([CH3:22])([CH3:21])[CH3:20]