Acetic Acid → 2-Bromo-1-(4-iodophenyl)ethanone
反応式
[I:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[O:10])[CH3:9])=[CH:4][CH:3]=1.C(O)(=O)C.[Br:15]Br>O>[Br:15][CH2:9][C:8]([C:5]1[CH:6]=[CH:7][C:2]([I:1])=[CH:3][CH:4]=1)=[O:10]参加物
5
反応条件
- 温度
- 15 °C
実験手順
Dissolving 20 g (81 mmol) of 4′-iodo acetophenone into 200 milliliter of acetic acid, and adding 12.8 g (81 mmol) of bromine while cooling with ice, stirred at the temperature of 15° C. for 3 hours. After the color of bromine disappeared, adding water and separating the precipitated solids by filtration, thereby obtained 27 g of crude 2-bromo-4′-iodo acetophenone.
後処理
- temperaturewhile cooling with ice
- customseparating the precipitated solids
- filtrationby filtration
出典と根拠
- ORDレコード
- ord-4f186ab3782a4e79825b256306f12e77
- 出典データセット
- uspto-grants-2011_01
- 特許番号
- US07867629B2
反応ノート
読み込み中…