Sodium Carbonate → 2-[4-(10-Bromo-9-anthracenyl)phenyl]imidazo[1,2-a]pyridine

関与物質

反応手順

Ten point six grams (33 mmol) of 2-(4-iodophenyl)-imidazo [1,2-a] pyridine, 10 g (33 mmol) of 10-bromoanthracene-9-boronic acid and 0.77 g of tetrakis (triphenylphosphine) palladium were dissolved into 100 milliliter of 1,2-dimethoxyethane, and adding 50 milliliter of 2.0M sodium carbonate aqueous solution, the resultant suspension was refluxed under heating for 7 hours. After completion of the reaction, separation with filtration was carried out and resultant crystals were washed with water and methanol, thereby obtaining 11.7 g of 2-[4-(10-bromo-anthracene-9-yl)-phenyl]-imidazo [1,2-a] pyridine (yield: 78%).

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