Methylhydrazine → 1-Methyl-3-(trifluoromethyl)-1H-pyrazole
反応式
C(O[CH:4]=[CH:5][C:6](=O)[C:7]([F:10])([F:9])[F:8])C.[CH3:12][NH:13][NH2:14]>CO>[CH3:12][N:13]1[CH:4]=[CH:5][C:6]([C:7]([F:10])([F:9])[F:8])=[N:14]1参加物
4
実験手順
To a mixture of 18 g of 4-ethoxy-1,1,1-trifluoro-3-butene-2-one and 50 ml of methanol was added 5.7 ml of methylhydrazine, and the mixture was heated to reflux for 4 hours. The reaction mixture was allowed to cool to room temperature, concentrated under reduced pressure, and subjected to distillation under reduced pressure (60° C./15 mmHg) to obtain 8.71 g of 1-methyl-3-trifluoromethyl-1H-pyrazole of the formula:
後処理
- temperaturethe mixture was heated
- temperatureto reflux for 4 hours
- concentrationconcentrated under reduced pressure
- distillationsubjected to distillation under reduced pressure (60° C./15 mmHg)
出典と根拠
- ORDレコード
- ord-649b69fbf3864b22ba70a0766c840c75
- 出典データセット
- uspto-grants-2011_01
- 特許番号
- US07867949B2
反応ノート
読み込み中…