関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Pyridinium chloride | HCID 10176127 | — |
| 反応物 | 6-Methoxy-1-benzothiophene | HCID 13634237 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | Benzo(b)thiophene-6-ol | HCID 88004 | 98.5% |
反応手順
6-Methoxybenzo[b]thiophene (6.15 g, 37.45 mmol) and pyridine hydrochloride (18.5 g) were heated together at 210° C. for 1 h. The mixture was cooled to 100° C., diluted with water (125 mL) and extracted with dichloromethane (3×70 mL). The combined extracts were washed with water (125 mL), dried (MgSO4) and evaporated in vacuo to give the title compound (5.54 g, 98%)
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07868017B2 |
|---|
| 出典データセット | uspto-grants-2011_01 |
|---|
| ORD ID | ord-5e1e09f2b3994491a6902c43b3fe3a66 |
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| 出典メモ | uspto-grants-2011_01 |
|---|
