化工社化工社 化学情報印刷レポート · 研究参考用
2-Bromo-3-methylthiophene → 2-(2-Methoxy-ethyl)-3-methyl-thiophene
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Bromo-3-methylthiophene | HCID 84314 | — |
| 反応物 | Ethanol, 2-methoxy-, 1-(4-methylbenzenesulfonate) | HCID 86977 | — |
| 生成物 | 2-(2-Methoxy-ethyl)-3-methyl-thiophene | HCID 66857153 | — |
反応手順
This compound was prepared analogous to Example 61, starting with 2-bromo-3-methylthiophene (1.5 g, 8.5 mmol) and toluene-4-sulfonic acid 2-methoxy-ethyl ester (2.9 g, 12.7 mmol, 1.5 equiv.) The crude product was purified on silica gel with eluent n-heptane and tert.butylmethyl ether. The title compound was obtained as a light yellow oil, 490 mg. GC-MS (EI): M=156
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07868030B2 |
| 出典データセット | uspto-grants-2011_01 |
| ORD ID | ord-6731e61c88124716ad4a635d0b337a3d |
| 出典メモ | uspto-grants-2011_01 |