Hydrochloric Acid → 3-Pyridinecarboxylic acid, 6-(4-amino-1-piperidinyl)-, ethyl ester
反応式
C(OC([NH:8][CH:9]1[CH2:14][CH2:13][N:12]([C:15]2[CH:20]=[CH:19][C:18]([C:21]([O:23][CH2:24][CH3:25])=[O:22])=[CH:17][N:16]=2)[CH2:11][CH2:10]1)=O)(C)(C)C.Cl>C(OCC)(=O)C>[NH2:8][CH:9]1[CH2:14][CH2:13][N:12]([C:15]2[CH:20]=[CH:19][C:18]([C:21]([O:23][CH2:24][CH3:25])=[O:22])=[CH:17][N:16]=2)[CH2:11][CH2:10]1参加物
4
実験手順
The product of stage b) is dissolved in ethyl acetate, a 3N solution of hydrochloric acid in ethyl acetate is added and the mixture is left stirring at ambient temperature for 10 hours. The product is filtered off and washed with acetone. The title product is obtained. M.p.: 148-150° C.
後処理
- waitthe mixture is left
- filtrationThe product is filtered off
- washwashed with acetone
出典と根拠
- ORDレコード
- ord-007fab9badaf4c7ca8c9d853d77769da
- 出典データセット
- uspto-grants-2005_02
- 特許番号
- US06858629B1
反応ノート
読み込み中…