Hydrochloric Acid → HCID 66887928、化合物

HRID 252379

反応式

HRID 252379 の反応式
[CH3:1][O:2][C:3](=[O:13])[C:4]([CH3:12])([C:6]1[CH:7]=[N:8][CH:9]=[CH:10][CH:11]=1)[CH3:5].[ClH:14]>CO.O.[Pt](=O)=O>[ClH:14].[CH3:1][O:2][C:3](=[O:13])[C:4]([CH3:5])([CH:6]1[CH2:11][CH2:10][CH2:9][NH:8][CH2:7]1)[CH3:12]

参加物

5

反応物 2

HCID 313Hydrochloric AcidHCID 54537815HCID 54537815、化合物

生成物 1

HCID 66887928HCID 66887928、化合物

試薬・触媒・溶媒 2

HCID 11139377Platinum dioxide monohydrate触媒HCID 887Methanol溶媒2 回

実験手順

A mixture of 0.823 g of 2-methyl-2-pyridin-3-yl-propionic acid methyl ester [476429-23-9] and 0.062 g of platinum(IV) oxide hydrate in 8 ml of methanol and 1.7 ml of 1.2M HCl in methanol at room temperature is hydrogenated for 5.5 hours. The catalyst is removed by filtration over Hyflo and the filtrate is concentrated by evaporation to provide the crude title compound as a brown oil which is used in the next step without further purification.

後処理

  1. customThe catalyst is removed by filtration over Hyflo
  2. concentrationthe filtrate is concentrated by evaporation

出典と根拠

ORDレコード
ord-6d202131da254efb96a29d25c4b84ec3
出典データセット
uspto-grants-2011_01
特許番号
US07868036B2

関連ノート

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