反応式
[I:1][C:2]1[C:10]2[C:5](=[CH:6][CH:7]=[C:8]([N+:11]([O-])=O)[CH:9]=2)[NH:4][N:3]=1.C(O)C.O.N>C(OCC)(=O)C.ClCCl>[NH2:11][C:8]1[CH:9]=[C:10]2[C:5](=[CH:6][CH:7]=1)[NH:4][N:3]=[C:2]2[I:1]参加物
6
実験手順
5-Amino-3-iodo-1H-indazole can be obtained as described in Example 4 from 1 g of 3-iodo-5-nitro-1H-indazole, 20 ml of ethanol, 6.9 g of ferrous sulfate, 10.8 ml of distilled water and 8.2 ml of 32% aqueous ammonia. 230 mg of 5-amino-3-iodo-1H-indazole are thus obtained in the form of a yellow foam (Rf=0.12, silica gel thin layer chromatography, eluent: ethyl acetate/dichloromethane (2/8 by volume)).
出典と根拠
- ORDレコード
- ord-99a073bb0a594f1b8fbc672a6e56d23e
- 出典データセット
- uspto-grants-2005_02
- 特許番号
- US06858638B2
関連ノート
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