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1H-Indazol-5-amine → 2-methylsulfonyl-N-(1H-indazol-5-yl)benzenesulfonamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1H-Indazol-5-amine | HCID 88012 | — |
| 反応物 | 2-Methanesulfonylbenzene-1-sulfonyl chloride | HCID 2735178 | — |
| 溶媒 | Pyridine | HCID 1049 | — |
| 生成物 | 2-methylsulfonyl-N-(1H-indazol-5-yl)benzenesulfonamide | HCID 11725502 | 24.3% |
反応手順
2-Methylsulfonyl-N-(1H-indazol-5-yl)benzenesulfonamide can be obtained as described in Example 2 from 1 g of 5-amino-1H-indazole, 20 ml of pyridine and 1.91 g of 2-methylsulfonylbenzenesulfonyl chloride. 0.64 g of 2-methylsulfonyl-N-(1H-indazol-5-yl)benzenesulfonamide is thus obtained in the form of a white solid melting at 245° C. (analysis C14H13N3O4S2 % calculated C, 47.85; H, 3.73; N, 11.96; O, 18.21; S, 18.25. % found C, 47.42; H, 3.72; N, 11.64; S, 17.97).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06858638B2 |
| 出典データセット | uspto-grants-2005_02 |
| ORD ID | ord-a83dd8035d0c4a56966a660df1fb3a5b |
| 出典メモ | uspto-grants-2005_02 |