tert-Butyl pentanoate → HCID 178444126、化合物

HRID 254123

反応式

HRID 254123 の反応式
[CH2:1]([C:3]1[CH:8]=[CH:7][C:6]([C@H:9]2[CH2:14][CH2:13][C@H:12]([CH:15]3[CH2:18][CH2:17][O:16]3)[CH2:11][CH2:10]2)=[CH:5][CH:4]=1)[CH3:2].[C:19]([O:25][C:26]([CH3:29])([CH3:28])[CH3:27])(=[O:24])[CH2:20][CH2:21][CH2:22][CH3:23]>>[CH2:21]([CH:20]([CH2:17][CH2:18][CH:15]([OH:16])[C@H:12]1[CH2:11][CH2:10][C@H:9]([C:6]2[CH:5]=[CH:4][C:3]([CH2:1][CH3:2])=[CH:8][CH:7]=2)[CH2:14][CH2:13]1)[C:19]([O:25][C:26]([CH3:28])([CH3:27])[CH3:29])=[O:24])[CH2:22][CH3:23]

参加物

3

反応物 2

HCID 520048tert-Butyl pentanoateHCID 178436316HCID 178436316、化合物

生成物 1

HCID 178444126HCID 178444126、化合物収率 93.2%

実験手順

Reaction operations were carried out according to the first step of Example 1 by using 2-(trans-4-(4-ethylphenyl)cyclohexyl)oxetane (42) (7.5 g, 30.9 mmol) and tert-butyl pentanoate (43) (15.6 g, 98.9 mmol) as starting materials to obtain tert-butyl 2-propyl-5-hydroxy-5-(trans-4-(4-ethylphenyl)cyclohexyl)pentanoate (44) (11.6 g, 28.8 mmol). The yield based on the compound (42) was 93%.

後処理

  1. customReaction operations

出典と根拠

ORDレコード
ord-6d3d2ac61f334cb58521a34cb0c6da8e
出典データセット
uspto-grants-2011_01
特許番号
US07875327B2

関連ノート

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