関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Bromine | HCID 24408 | — |
| 反応物 | 8,9-Dihydrocyclopenta[def]phenanthrene | HCID 605749 | — |
| 溶媒 | Carbon Tetrachloride | HCID 5943 | — |
| 生成物 | 2-bromo-8,9-dihydro-4H-cyclopenta[def]phenanthrene | HCID 12524363 | 83.3% |
反応手順
8,9-dihydro-4H-cyclopenta[def]phenanthrene (4.0 g, 20.8 mmol) was put into a 250 ml round bottom flask (RBF), and CCl4 (100 ml) was added thereto. The reaction mixture was cooled to 0° C., and Br2 (3.3 g, 20.8 mmol) was dropwise added thereto. The reaction solution was incubated for 4 hours and a 10% NaSO3 solution was added thereto. The organic phase was separated, concentrated under a reduced pressure, and recrystallized from n-hexane to obtain 4.7 g of a 2-bromo-8,9-dihydro-4H-cyclopenta[def]phenanthrene compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07875367B2 |
|---|
| 出典データセット | uspto-grants-2011_01 |
|---|
| ORD ID | ord-59c6361377d046c5afbbdd3118e3e552 |
|---|
| 出典メモ | uspto-grants-2011_01 |
|---|
